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-5/5q Deletion
Method
Units
Reference Range
FISH
Specimen Requirements
Preferred
No
Type
Volume
Temperature/Stability
1
Bone marrow sodium heparin (green top)
1-2 mL
Room temperature; for overnight storage refrigerate; transport with refrigerated cold pack
Alternate
No
Type
Volume
Temperature/Stability
1
Whole blood sodium heparin (green top)
3-5 mL
Room temperature; for overnight storage refrigerate; transport with refrigerated cold pack
General Information
Clinical Utility
For the detection of -5/5q deletion to aid in the assessment of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Deletion 5q is present in about 10 to15 percent of de novo MDS patients and in as many as 50 percent of therapy-related MDS. 5q deletion, as a sole abnormality, confers a favorable prognosis.
Set Up Schedule
Monday - Friday
Turnaround Time
3 days
CPT Codes
FDA Status
ASR
Notes
References
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