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t(9;22) [BCR/ABL1] and del(9)(q34)
Method
Units
Reference Range
FISH
Specimen Requirements
Preferred
No
Type
Volume
Temperature/Stability
1
Bone marrow sodium heparin (green top)
1-2 mL
Room temperature; for overnight storage refrigerate; transport with refrigerated cold pack
Alternate
No
Type
Volume
Temperature/Stability
1
Whole blood sodium heparin (green top)
3-5 mL
Room temperature; for overnight storage refrigerate; transport with refrigerated cold pack
General Information
Clinical Utility
Used in conjunction with standard cytogenetics for diagnosis of CML. Used to confirm BCR/ABL1 fusion in Philadelphia chromosome-negative CML;it includes 9q34 probe to identify deletions of prognostic importance.
Set Up Schedule
Monday - Friday
Turnaround Time
3 days
CPT Codes
88271x2, 88275, 88291
FDA Status
ASR
Notes
References
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