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Chromosome Analysis with Reflex to FISH
Method
Units
Reference Range
Cytogenetics
Specimen Requirements
Preferred
No
Type
Volume
Temperature/Stability
1
Bone marrow sodium heparin (green top)
2-3 mL
Room temperature; for overnight storage refrigerate; transport with refrigerated cold pack
Alternate
No
Type
Volume
Temperature/Stability
1
Whole blood with immature forms sodium heparin (green top)
2-5 mL
Room temperature; for overnight storage refrigerate; transport with refrigerated cold pack
General Information
Clinical Utility
Karyotype analysis identifies acquired chromosomal abnormalities associated with leukemia, lymphoma, myeloproliferative disorders such as CML, and various myelodysplastic syndromes (MDS) with reflex to FISH if cytogenetic analysis is limited or does not correlate with morphologic/flow findings.
Set Up Schedule
Monday-Saturday
Turnaround Time
5-7 days
CPT Codes
FDA Status
FISH-ASR
Notes
References
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